Freeboot

verb
Recreational use of the anti-cancer drug Reboot™ for the purpose of experiencing its notable gender-reassignment side effect.
Source
Changes

Downwell

adjective
Short form of the phrase “down the gravity well” – i.e. located on the surface of a planet.
adverb
From orbit to the surface of a planet.
Source
Accelerando

Databall

noun
An encapsulated message sent over a digital communications network.
Source
The Girl Who Was Plugged In

Autodarwinate

verb
To commit evolutionary self-deselection (suicide).
Origin
Charles Darwin; evolution of species by natural selection.
Source
Accelerando

Sensawunda

noun informal
A street drug that stimulates rapid cognition, having novotrophin-B and MDMA as ingredients.
Origin
Phonetic transcription of “sense-a-wonder”.
Source
Accelerando

Metacortex

noun
A distributed cloud of software agents that augments the computational power of the human brain.
Source
Accelerando

Vibrocalyx

noun
The vibrating outermost flower part of a choro-flora, a plant that uses sonic stimulation to attract pollinating creatures.
Source
Prima Belladonna

Robotics

noun
A branch of technology dealing with the design, construction, operation, and application of robots.
Source
Liar!

Verdash

verb
To regret.
Source
Of Time and Third Avenue

Thisney

adjective
Boring.
Source
Of Time and Third Avenue

Girlygirl

noun
A professionally flirtatious hostess, akin to a geisha.
Source
The Ballad of Lost C’mell

Tempunaut

noun
Crewman aboard a time-travelling vessel.
Origin
Derived from tempus (time) and nautēs (sailor).
Source
A Little Something for Us Tempunauts